WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H558564
CAS#: 139-13-9
Description: Nitrilotriacetic acid is a chelating agent. It is also used as a complexing agent, metal masking agent.
Hodoodo Cat#: H558564
Name: Nitrilotriacetic acid
CAS#: 139-13-9
Chemical Formula: C6H9NO6
Exact Mass: 191.04
Molecular Weight: 191.139
Elemental Analysis: C, 37.70; H, 4.75; N, 7.33; O, 50.22
This product is not in stock, which may be available by custom synthesis.
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Synonym: Nitrilotriacetic acid; Nitriloacetate; Nitrilotriacetate;
IUPAC/Chemical Name: Glycine, N,N-bis(carboxymethyl)-
InChi Key: MGFYIUFZLHCRTH-UHFFFAOYSA-N
InChi Code: InChI=1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)
SMILES Code: O=C(O)CN(CC(O)=O)CC(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 191.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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11: Watson DS, Platt VM, Cao L, Venditto VJ, Szoka FC Jr. Antibody response to polyhistidine-tagged peptide and protein antigens attached to liposomes via lipid-linked nitrilotriacetic acid in mice. Clin Vaccine Immunol. 2011 Feb;18(2):289-97. doi: 10.1128/CVI.00425-10. Epub 2010 Dec 15. PubMed PMID: 21159923; PubMed Central PMCID: PMC3067350.
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16: Soleimani M, Hajabbasi MA, Afyuni M, Akbar S, Jensen JK, Holm PE, Borggaard OK. Comparison of natural humic substances and synthetic ethylenediaminetetraacetic acid and nitrilotriacetic acid as washing agents of a heavy metal-polluted soil. J Environ Qual. 2010 Apr 13;39(3):855-62. doi: 10.2134/jeq2009.0292. Print 2010 May-Jun. PubMed PMID: 20400581.
17: Padala AN, Bhaskarapillai A, Velmurugan S, Narasimhan SV. Sorption behaviour of Co(II) and Cu(II) on chitosan in presence of nitrilotriacetic acid. J Hazard Mater. 2011 Jul 15;191(1-3):110-7. doi: 10.1016/j.jhazmat.2011.04.046. Epub 2011 Apr 16. PubMed PMID: 21592656.
18: Ansar S, Iqbal M. Ascorbic acid inhibits ferric nitrilotriacetate induction of ornithine decarboxylase, DNA synthesis, oxidative stress, and hepatotoxicity in rats. Toxicol Ind Health. 2015 Nov;31(11):1008-14. doi: 10.1177/0748233713493824. Epub 2013 Jul 17. PubMed PMID: 23863956.
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