WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H573165
CAS#: 2610-86-8 (potassium)
Description: Warfarin potassium, also known as Coumadin, is an anticoagulant. It is used to treat blood clots such as deep vein thrombosis and pulmonary embolism and to prevent stroke in people who have atrial fibrillation, valvular heart disease or artificial heart valves.
Hodoodo Cat#: H573165
Name: Warfarin potassium
CAS#: 2610-86-8 (potassium)
Chemical Formula: C19H15KO4
Exact Mass: 346.06
Molecular Weight: 346.420
Elemental Analysis: C, 65.88; H, 4.36; K, 11.29; O, 18.47
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Related CAS #: 129-06-6 (sodium) 81-81-2 (free acid) 2610-86-8 (potassium)
Synonym: Antrombin K, Coumadin, Warfarin K, Warfarin potassium
IUPAC/Chemical Name: 3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin potassium salt
InChi Key: WSHYKIAQCMIPTB-UHFFFAOYSA-M
InChi Code: 1S/C19H16O4.K/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1
SMILES Code: CC(=O)CC(c1ccccc1)c2c(c3ccccc3oc2=O)[O-].[K+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
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The following data is based on the product molecular weight 346.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Jeraj L, Jezovnik MK, Poredos P. Rivaroxaban versus warfarin in the prevention of post-thrombotic syndrome. Thromb Res. 2017 Sep;157:46-48. doi: 10.1016/j.thromres.2017.05.029. Epub 2017 May 29. PubMed PMID: 28692839.
2: Sarratt SC, Nesbit R, Moye R. Safety Outcomes of Apixaban Compared With Warfarin in Patients With End-Stage Renal Disease. Ann Pharmacother. 2017 Jun;51(6):445-450. doi: 10.1177/1060028017694654. Epub 2017 Feb 1. PubMed PMID: 28478715.
3: Ruff CT, Giugliano RP, Braunwald E, Hoffman EB, Deenadayalu N, Ezekowitz MD, Camm AJ, Weitz JI, Lewis BS, Parkhomenko A, Yamashita T, Antman EM. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014 Mar 15;383(9921):955-62. doi: 10.1016/S0140-6736(13)62343-0. Epub 2013 Dec 4. PubMed PMID: 24315724.
