WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H564867
CAS#: NONE
Description: NY0116 is an agonist of neuromedin U receptor 2 (NMUR2) which decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells.
Hodoodo Cat#: H564867
Name: NY0116
CAS#: NONE
Chemical Formula: C22H23N3O
Exact Mass: 345.18
Molecular Weight: 345.450
Elemental Analysis: C, 76.49; H, 6.71; N, 12.16; O, 4.63
This product is not in stock, which may be available by custom synthesis.
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Synonym: NY-0116; NY 0116; NY0116
IUPAC/Chemical Name: 1-(2-(Trityloxy)ethyl)guanidine
InChi Key: FZXFGYLHTRBHNJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H23N3O/c23-21(24)25-16-17-26-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H4,23,24,25)
SMILES Code: NC(NCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 345.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Sampson CM, Kasper JM, Felsing DE, Raval SR, Ye N, Wang P, Patrikeev I, Rytting E, Zhou J, Allen JA, Hommel JD. Small-Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models. Pharmacol Res Perspect. 2018 Aug 23;6(5):e00425. doi: 10.1002/prp2.425. eCollection 2018 Oct. PubMed PMID: 30151213; PubMed Central PMCID: PMC6106167.