WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H565148
CAS#: 162280-51-5 (HCl)
Description: S18616 Hydrochloride is a selective and highly potent alpha2-adrenoceptor agonist.
Hodoodo Cat#: H565148
Name: S18616 Hydrochloride
CAS#: 162280-51-5 (HCl)
Chemical Formula: C12H14Cl2N2O
Exact Mass: 272.05
Molecular Weight: 273.160
Elemental Analysis: C, 52.77; H, 5.17; Cl, 25.96; N, 10.26; O, 5.86
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 162280-52-6 (free base) 162280-51-5 (HCl) 757917-26-3 (R-isomer) 162280-55-9 (R-isomer HCl) 791561-41-6 (S-isomer) 162280-56-0 (S-isomer HCl)
Synonym: S18616 Hydrochloride; S18616 HCl; S18616; S-18616; S 18616;
IUPAC/Chemical Name: 8-chloro-3,4-dihydro-1H,5'H-spiro[naphthalene-2,4'-oxazol]-2'-amine hydrochloride
InChi Key: HWKMDOVCWAVYIB-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H13ClN2O.ClH/c13-10-3-1-2-8-4-5-12(6-9(8)10)7-16-11(14)15-12;/h1-3H,4-7H2,(H2,14,15);1H
SMILES Code: NC(OC1)=NC21CCC3=C(C(Cl)=CC=C3)C2.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 273.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Millan MJ, Dekeyne A, Papp M, La Rochelle CD, MacSweeny C, Peglion JL, Brocco M. S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J Pharmacol Exp Ther. 2001 Aug;298(2):581-91. PubMed PMID: 11454919.