WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H565445
CAS#: 675104-49-1 (free base)
Description: SSYA10-001, also known as DSHS 00884 and CCG-45281, a non-toxic human papillomavirus E6 inhibitor and is a replication inhibitor of severe acute respiratory syndrome (SARS), mouse hepatitis, and Middle East respiratory syndrome coronaviruses.
Hodoodo Cat#: H565445
Name: SSYA10-001
CAS#: 675104-49-1 (free base)
Chemical Formula: C12H12N4O2S2
Exact Mass: 308.04
Molecular Weight: 308.370
Elemental Analysis: C, 46.74; H, 3.92; N, 18.17; O, 10.38; S, 20.79
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Related CAS #: 675104-49-1 (free base) SSYA10-001 HCl
Synonym: SSYA10001; SSYA10 001; SSYA10-001; DSHS00884; DSHS-00884; DSHS 00884; CCG-45281; CCG 45281; CCG45281;
IUPAC/Chemical Name: 3-[(2-Nitrophenyl)sulfanylmethyl]-4-prop-2-enyl-1H-1,2,4-triazole-5-thione
InChi Key: VWFIHGWHMXSTAO-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H12N4O2S2/c1-2-7-15-11(13-14-12(15)19)8-20-10-6-4-3-5-9(10)16(17)18/h2-6H,1,7-8H2,(H,14,19)
SMILES Code: S=C1N(CC=C)C(CSC2=CC=CC=C2[N+]([O-])=O)=NN1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 308.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrob Agents Chemother. 2014 Aug;58(8):4894-8. doi: 10.1128/AAC.02994-14. Epub 2014 May 19. PubMed PMID: 24841268; PubMed Central PMCID: PMC4136041.
2: Adedeji AO, Singh K, Calcaterra NE, DeDiego ML, Enjuanes L, Weiss S, Sarafianos SG. Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase. Antimicrob Agents Chemother. 2012 Sep;56(9):4718-28. doi: 10.1128/AAC.00957-12. Epub 2012 Jun 25. PubMed PMID: 22733076; PubMed Central PMCID: PMC3421890.