WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H534638
CAS#: 14334-41-9
Description: Pramiverin HCl is a bioactive chemical.
Hodoodo Cat#: H534638
Name: Pramiverin HCl
CAS#: 14334-41-9
Chemical Formula: C21H28ClN
Exact Mass: 329.19
Molecular Weight: 329.912
Elemental Analysis: C, 76.45; H, 8.56; Cl, 10.75; N, 4.25
Synonym: Pramiverin HCl
IUPAC/Chemical Name: 4,4-Diphenyl-N-isopropylcyclohexylamine hydrochloride
InChi Key: BMBNXHMQMNPCIV-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H27N.ClH/c1-17(2)22-20-13-15-21(16-14-20,18-9-5-3-6-10-18)19-11-7-4-8-12-19;/h3-12,17,20,22H,13-16H2,1-2H3;1H
SMILES Code: CC(NC1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)CC1)C.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 329.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Morel CJ. Empleo del anticolinérgico y antiespasmódico pramiverin (HSp 2986, E. Merck) para obtener vagotomía médica [Use of the anticholinergic and antispasmodic agent pramiverin (HSp 2986, E. Merck) to obtain medical vagotomy]. Rev Esp Enferm Apar Dig. 1974 Jan 1;42(1):73-80. Spanish. PMID: 4460118.
2: Carrillo Mancero LA. Pramiverina-metamizol (1): nueva fórmula para el control del cólico de origen digestivo [Pramiverin-metamizole: new formula for the control of colic of gastrointestinal origin]. G E N. 1977 Apr-Jun;31(4):421-6. Spanish. PMID: 97151.
3: Enenkel HJ, Müller-Calgan H, Schorscher E. Zur cholinolytischen Wirkung von Pramiverin [On the cholinolytic activity of pramiverine]. Arzneimittelforschung. 1976 Apr;26(4b):690-6. German. PMID: 821493.
4: Diekmann HW, Bühring KU, Garbe A, Nowak H. Metabolismus von Pramiverin [Metabolism of pramiverine (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):722-6. German. PMID: 821495.
5: Eberstein M, Frohberg H, Hofmann A, Jochmann G, Metallinos A, Schiling B, Weisse G. Toxikologische Prüfung von Pramiverin [Toxicological study on pramiverine (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):703-9. German. PMID: 989019.
6: Romero HE, Fernández AC, Rosales TC. Wirkung der Kombination Pramiverin/Metamizol bei kolikartigen Schmerzzuständen [The effect of the combination pramiverine/metamizole in colic pain (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):738-40. German. PMID: 989023.
7: Koch E, Eisele W. Therapieergebnisse mit der Kombination Pramiverin/metamizol in einem Feldversuch [Therapeutic results with the combination pramiverine/metamizole in a multicentre trial (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):745-52. German. PMID: 782472.
8: Morel CJ. Experimentelle Untersuchungen mit Pramiverin [Experimental studies on pramiverine (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):699-702. German. PMID: 989018.
9: Koch E. Zusammenfassung der Ergebnisse klinischer und experimenteller Untersuchungen mit Pramiverin und Pramiverin/Metamizol [Profile comment on clinical and experimental studies of pramiverine and pramiverine/metamizole (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4b):686-9. German. PMID: 782469.
10: Steiner K, Garbe A. Organverteilung von 14C-Pramiverin im Organismus der Ratte [Organ distribution of 14C-pramiverine in the rat]. Arzneimittelforschung. 1976 Apr;26(4b):709-16. German. PMID: 989020.
