Protokylol hydrochloride
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Hodoodo CAT#: H412459

CAS#: 136-69-6 (HCl)

Description: Protokylol hydrochloride is the salt form of Protokylol (free base) (Asmetil, Caytine, Palison, Ventaire), a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. It is methylenedioxyphenyl-isoproterenol.


Chemical Structure

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Protokylol hydrochloride
CAS# 136-69-6 (HCl)

Theoretical Analysis

Hodoodo Cat#: H412459
Name: Protokylol hydrochloride
CAS#: 136-69-6 (HCl)
Chemical Formula: C18H22ClNO5
Exact Mass: 0.00
Molecular Weight: 367.830
Elemental Analysis: C, 58.78; H, 6.03; Cl, 9.64; N, 3.81; O, 21.75

Price and Availability

Size Price Availability Quantity
5mg USD 500 2 Weeks
25mg USD 950 2 Weeks
100mg USD 2050 2 Weeks
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Related CAS #: 136-69-6 (HCl)   136-70-9 (free base)  

Synonym: Protokylol hydrochloride; NSC113490; NSC-113490; NSC 113490

IUPAC/Chemical Name: 1,2-Benzenediol, 4-(2-((2-(1,3-benzodioxol-5-yl)-1-methylethyl)amino)-1-hydroxyethyl)-, hydrochloride (9CI)

InChi Key: LOVXREQUMZKFCM-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H21NO5.ClH/c1-11(6-12-2-5-17-18(7-12)24-10-23-17)19-9-16(22)13-3-4-14(20)15(21)8-13;/h2-5,7-8,11,16,19-22H,6,9-10H2,1H3;1H

SMILES Code: OC1=CC=C(C(O)CNC(C)CC2=CC=C(OCO3)C3=C2)C=C1O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 367.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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9: Scriabine A, Rival J, Bellet S, Morgan G Jr, Weyn AS, Nusbaum M. Effect of protokylol on the ventricular rate in dogs with experimental A-V heart block. Am Heart J. 1969 May;77(5):649-52. PubMed PMID: 5778054.

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