WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H412741
CAS#: 76906-79-1
Description: Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.
Hodoodo Cat#: H412741
Name: Prisotinol
CAS#: 76906-79-1
Chemical Formula: C11H18N2O
Exact Mass: 194.14
Molecular Weight: 194.280
Elemental Analysis: C, 68.01; H, 9.34; N, 14.42; O, 8.24
This product is not in stock, which may be available by custom synthesis.
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Synonym: Prisotinol; CGS5649B; CGS 5649B; CGS-5649B
IUPAC/Chemical Name: 3-Pyridinol, 6-(2-((1-methylethyl)amino)propyl)-
InChi Key: WQRPBKUCJBWQRT-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3
SMILES Code: OC1=CC=C(CC(NC(C)C)C)N=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 194.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Molloy DW, Guyatt GH, Standish T, Willan A, McIlroy W, D'Souza J, Brown G, Mondadori C. Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia. J Gen Intern Med. 1993 Aug;8(8):444-7. doi: 10.1007/BF02599624. PMID: 8410411.
2: Mondadori C, Ducret T, Borkowski J. How long does 'memory consolidation' take? New compounds can improve retention performance, even if administered up to 24 hours after the learning experience. Brain Res. 1991 Jul 26;555(1):107-11. doi: 10.1016/0006-8993(91)90866-t. PMID: 1933323.
3: Nilsson E, Schneider T, Hoffmann E, Schmidt EK. Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man. Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:201-4. PMID: 1820879.
