WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H208072
CAS#: 2133417-13-5
Description: Ralmitaront is a TAAR1 agonist for schizophrenia.
Hodoodo Cat#: H208072
Name: Ralmitaront
CAS#: 2133417-13-5
Chemical Formula: C17H22N4O2
Exact Mass: 314.17
Molecular Weight: 314.389
Elemental Analysis: C, 64.95; H, 7.05; N, 17.82; O, 10.18
This product is not in stock, which may be available by custom synthesis.
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Synonym: Ralmitaront
IUPAC/Chemical Name: (R)-5-ethyl-4-methyl-N-(4-(morpholin-2-yl)phenyl)-1H-pyrazole-3-carboxamide
InChi Key: XHHXGKRFUPEPFM-HNNXBMFYSA-N
InChi Code: InChI=1S/C17H22N4O2/c1-3-14-11(2)16(21-20-14)17(22)19-13-6-4-12(5-7-13)15-10-18-8-9-23-15/h4-7,15,18H,3,8-10H2,1-2H3,(H,19,22)(H,20,21)/t15-/m0/s1
SMILES Code: O=C(C1=NNC(CC)=C1C)NC(C=C2)=CC=C2[C@@H]3CNCCO3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 314.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1. Dedic N, Dworak H, Zeni C, Rutigliano G, Howes OD. Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies. Int J Mol Sci. 2021 Dec 7;22(24):13185. doi: 10.3390/ijms222413185. PMID: 34947997; PMCID: PMC8704992.
2. Kantrowitz JT. Trace Amine-Associated Receptor 1 as a Target for the Development of New Antipsychotics: Current Status of Research and Future Directions. CNS Drugs. 2021 Nov;35(11):1153-1161. doi: 10.1007/s40263-021-00864-3. Epub 2021 Oct 15. PMID: 34655036.
