WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H112061
CAS#: 316371-84-3 (potassium)
Description: Rosiglitazone activates PPARγ1 and PPARγ2 and selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM and can induce differentiation of C3H10T1/2 stem cells into adipocytes when used at a concentration of 1 µM.
Hodoodo Cat#: H112061
Name: Rosiglitazone potassium
CAS#: 316371-84-3 (potassium)
Chemical Formula: C18H18KN3O3S
Exact Mass: 0.00
Molecular Weight: 395.520
Elemental Analysis: C, 54.66; H, 4.59; K, 9.89; N, 10.62; O, 12.14; S, 8.11
Related CAS #: 155141-29-0 (maleate) 122320-73-4 (free base) 316371-84-3 (potassium)
Synonym: Rosiglitazone (potassium salt); Rosiglitazone K; Rosiglitazone (K)
IUPAC/Chemical Name: potassium 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)-2,4-dioxothiazolidin-3-ide
InChi Key: RWOGCLSZSSKLEN-UHFFFAOYSA-M
InChi Code: InChI=1S/C18H19N3O3S.K/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);/q;+1/p-1
SMILES Code: CN(C1=NC=CC=C1)CCOC2=CC=C(C=C2)CC3SC([N-]C3=O)=O.[K+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
Ethanol | 2.0 | 5.06 | |
H2O | 1.0 | 2.53 |
The following data is based on the product molecular weight 395.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |