Cefaclor
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Hodoodo CAT#: H317379

CAS#: 53994-73-3 (free)

Description: Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic that inhibits cell wall synthesis. The antibiotic is active against a wide spectrum of common pathogens, including gram-positive and gram-negative bacteria. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

Chemical Structure

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Cefaclor
CAS# 53994-73-3 (free)
Instruction

Theoretical Analysis

Hodoodo Cat#: H317379
Name: Cefaclor
CAS#: 53994-73-3 (free)
Chemical Formula: C15H14ClN3O4S
Exact Mass: 367.04
Molecular Weight: 367.810
Elemental Analysis: C, 48.98; H, 3.84; Cl, 9.64; N, 11.42; O, 17.40; S, 8.72

Price and Availability

Size Price Availability Quantity
100mg USD 250 2 Weeks
1g USD 650 2 Weeks
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Related CAS #: 70356-03-5 (hydrate)   53994-73-3 (free)   91828-55-6 (salt)  

Synonym: Cefaclor; Ceclor; Cefaclorum; Cephaclor; Raniclor; Kefral; S6472; Cefaclor Anhydrous; Cefaclor Monohydrate; Keclor; Lilly 99638; Monohydrate, Cefaclor; S 6472; S-6472;

IUPAC/Chemical Name: (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChi Key: QYIYFLOTGYLRGG-GPCCPHFNSA-N

InChi Code: InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1

SMILES Code: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 367.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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