WAY-123398 free base

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H526568

CAS#: 138490-53-6 (free base)

Description: Way 123398 is a class III antiarrhythmic agent.

Chemical Structure

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WAY-123398 free base
CAS# 138490-53-6 (free base)
Instruction

Theoretical Analysis

Hodoodo Cat#: H526568
Name: WAY-123398 free base
CAS#: 138490-53-6 (free base)
Chemical Formula: C19H25N5O4S
Exact Mass: 451.13
Molecular Weight: 451.560
Elemental Analysis: C, 50.54; H, 5.58; N, 15.51; O, 14.17; S, 14.20

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 138490-52-5 (HCl)   139702-24-2 (2HCl)   138490-53-6 (free base)    

Synonym: Way123398; Way-123398; Way 123398; Way-123,398; Way123,398; Way 123,398

IUPAC/Chemical Name: N-methyl-N-(2-(methyl(1-methyl-1H-benzo[d]imidazol-2-yl)amino)ethyl)-4-(methylsulfonamido)benzenesulfonamide

InChi Key: PELVIWZRAPOYAC-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H25N5O4S2/c1-22(19-20-17-7-5-6-8-18(17)24(19)3)13-14-23(2)30(27,28)16-11-9-15(10-12-16)21-29(4,25)26/h5-12,21H,13-14H2,1-4H3

SMILES Code: O=S(C1=CC=C(NS(=O)(C)=O)C=C1)(N(C)CCN(C)C2=NC3=CC=CC=C3N2C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 451.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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12: Selyanko AA, Hadley JK, Wood IC, Abogadie FC, Delmas P, Buckley NJ, London B, Brown DA. Two types of K(+) channel subunit, Erg1 and KCNQ2/3, contribute to the M-like current in a mammalian neuronal cell. J Neurosci. 1999 Sep 15;19(18):7742-56. PubMed PMID: 10479678.

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15: Spinelli W, Parsons RW, Colatsky TJ. Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol. 1992 Dec;20(6):913-22. PubMed PMID: 1282594.

16: Becchetti A, De Fusco M, Crociani O, Cherubini A, Restano-Cassulini R, Lecchi M, Masi A, Arcangeli A, Casari G, Wanke E. The functional properties of the human ether-à-go-go-like (HELK2) K+ channel. Eur J Neurosci. 2002 Aug;16(3):415-28. PubMed PMID: 12193184.