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Newest Products
NCGC00244536
CAT#: H561403
CAS#: 2003260-55-5
KDM4B-IN-B3, also know as NCGC00244536, is a novel KDM4 inhibitor. KDM4B-IN-B3 inhibits the in vivo growth of tumors derived from PC3 cells and ex v…
AVN-101 HCl
CAT#: H561401
CAS#: 1061354-48-0 (HCl)
AVN-101 is a very potent 5-HT7 receptor antagonist, with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors. It is a milti-target drug…
Cetraxate HCl
CAT#: H329822
CAS#: 27724-96-5 (HCl)
Cetraxate, also known as DV-1006, is a mucosal protective agent and an anti-ulcer drug candidate. It is a tautomer of a cetraxate zwitterion. Cetraxa…
NVS-PAK1-1
CAT#: H561311
CAS#: 1783816-74-9
NVS-PAK1-1 is a specific allosteric PAK1 inhibitor.
DCG066
CAT#: H561309
CAS#: 494786-13-9
DCG066 is a G9a inhibitor. DCG066 can bind directly to G9a and inhibit methyltransferase activity in vitro. It displays low cytotoxicity in leukemia c…
Xanthohumol
CAT#: H561308
CAS#: 6754-58-1
Xanthohumol is under basic research for its potential chemopreventive and anti-restenotic properties. Xanthohumol shows anti mutagenic activity agains…
ProTAME
CAT#: H561291
CAS#: 1362911-19-0
ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significant…
PHPS1
CAT#: H561287
CAS#: 314291-83-3
PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 m…
KC01
CAT#: H561252
CAS#: 1646795-59-6
KC01 is a covalent inhibitor of ABHD16A. ABHD16A is a phosphatidylserine (PS) lipase that generates lyso-PS in mammalian systems. KC01 can deplete lys…
CYM-5478
CAT#: H561234
CAS#: 870762-83-7
CYM-5478 is a potent, selective agonist for S1P2. Under nutrient-deprivation stress produced by serum-starvation, CYM-5478 induced a statistically sig…
NSC348884
CAT#: H561190
CAS#: 81624-55-7
NSC348884 is a nucleophosmin inhibitor. NSC348884 also disrupts oligomer formation and induces apoptosis in human cancer cells.
PT2399
CAT#: H561185
CAS#: 1672662-14-4
PT2399 is a first-in-class, orally available, small molecule inhibitor of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β…
OUL35
CAT#: H561162
CAS#: 6336-34-1
OUL35, also known as NSC39047, is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10…
AS-8351
CAT#: H561158
CAS#: 796-42-9
AS-8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
E6446
CAT#: H561151
CAS#: 1219925-73-1 (free base)
E6446 is a TLR inhibitor. E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibit…
Petesicatib
CAT#: H561126
CAS#: 1252637-35-6
Petesicatib, also known as RG-7625 and RO-5459072, is a cathepsin inhibitor drug candidate. CatS activity was significantly elevated in tear fluid, b…
Parsaclisib HCl
CAT#: H206961
CAS#: 1995889-48-9 (HCl)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes with PIM protein kinase inhibition to cause tumor regression in a …
C188-9
CAT#: H540229
CAS#: 432001-19-9
C188-9, also known as TTI-101, is a STAT3 inhibitor. HDM-induced airway inflammation, remodeling, and Th2/Th17-type cell accumulation involve STAT3 a…
Fulacimstat
CAT#: H561116
CAS#: 1488354-15-9
Fulacimstat, also known as BAY1142524, is a chymase inhibitor and antifibrotic drug candidate with IC50 of 4 nM and 3 nM for human and hamster chymas…
Elsulfavirine
CAT#: H561112
CAS#: 868046-19-9
Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of…
Delgocitinib
CAT#: H561108
CAS#: 1263774-59-9 (free)
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic …
R-IMPP
CAT#: H561048
CAS#: 2133832-83-2 (free base)
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels o…
SF2312
CAT#: H561044
CAS#: 107729-45-3
SF2312 is an enolase inhibitor. SF2312 is a phosphonate antibiotic of unknown mode of action produced by the actinomycete Micromonospora, which is act…
S38093 HCl
CAT#: H561026
CAS#: 1222097-72-4 (HCl)
S38093 is an inverse agonist at histamine H3 receptors. S38093 has no affinity for other histaminergic receptors.
CRT0273750
CAT#: H561009
CAS#: 1979939-16-6
CRT0273750 is an autotaxin inhibitor. CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies. CRT0273750 has an unexpected bind…
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