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Newest Products
Pyrimorph
CAT#: H561001
CAS#: 868390-90-3
Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of…
BI-894999
CAT#: H206845
CAS#: 1660117-38-3
BI-894999 is a potent and selective BET inhibitor potentially useful for the Treatment of hematological malignancies by repression of super-enhancer d…
UMK57
CAT#: H526400
CAS#: 342595-74-8
UMK57 is a novel inhibitor of chromosomal instability, potentiating MCAK in vivo and transiently suppressing chromosome mis-segregation in CIN cancer …
AG-7404
CAT#: H530656
CAS#: 343565-99-1
AG-7404 is a potent protease inhibitor with Anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.6…
SKL2001 free base
CAT#: H526260
CAS#: 909089-13-0
SKL-2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β…
SU16F
CAT#: H526130
CAS#: 251356-45-3
SU16F is a potent and selective platelet-derived growth factor receptor ß (PDGFRß) inhibitor. SU16f inhibits fibrotic scar formation and facilitates a…
SU1498
CAT#: H407492
CAS#: 168835-82-3
SU1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM).
5-BDBD
CAT#: H525918
CAS#: 768404-03-1
5-BDBD is a selective inhibitor of P2X4.
Autophinib
CAT#: H525896
CAS#: 1644443-47-9
Autophinib is a novel potent autophagy inhibitor, inhibiting autophagy induced by starvation or Rapamycin by targeting the lipid kinase VPS34.
OX02983
CAT#: H525869
CAS#: N/A
OX02983 is a novel anthelmintic agent, immobilising whipworm and reducing the ability of embryonated T. muris eggs to establish infection in the mouse…
VU-1545
CAT#: H532950
CAS#: 890764-63-3
VU 1545 is a positive allosteric modulator of metabotropic glutamate receptor type 5 (mGluR-5) (EC50 = 9.6 nM, Ki = 156 nM at rat mGluR-5).
VU0463597
CAT#: H532947
CAS#: 1382481-79-9
VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactiv…
VU0119498
CAT#: H532894
CAS#: 79183-37-2
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM). VU0119498 is a neuroprotective…
LDN-0212320 Maleate
CAT#: H525692
CAS#: 894002-50-7
LDN-0212320 Maleate is a novel activator of glutamate transporter EAAT2 translation.
YL-0919
CAT#: H525690
CAS#: 1339058-04-6
YL-0919 is a novel 5-HT1A receptor agonist and selective serotonin reuptake inhibitor.
F1063-0967
CAT#: H525607
CAS#: 613225-56-2
F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
Brassinin
CAT#: H540050
CAS#: 105748-59-2
Brassinin is an indoleamine-2,3-dioxygenase inhibitor found in cruciferous vegetables. It induces cell cycle arrest and apoptosis in prostate cancer c…
PaPE-1
CAT#: H525459
CAS#: 2107327-36-4 (S-isomer)
PaPE-1 is a pathway Preferential Estrogen, activating the extranuclear signaling pathway without activity on the nuclear signaling pathway. PaPE-1 eli…
Rbin-2
CAT#: H525447
CAS#: 2032282-97-4
Rbin-2 is a novel cell penetrant, potent, selective and reversible inhibitor of Midasin, inhibiting eukaryotic ribosome biogenesis and directly target…
ATPO
CAT#: H525387
CAS#: 252930-37-3
ATPO is a potent and Selective Ampa Receptor Antagonist.
IWP-L6
CAT#: H407489
CAS#: 1427782-89-5
IWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.5 nM). Porcupine is a member of the …
ST-1006
CAT#: H532796
CAS#: 1196994-11-2 (free base)
ST-1006 is a histamine H4 receptor agonist (H4R agonist). ST-1006 alleviates neuropathic pain through differential regulation of ERK, JNK, and P38 MA…
SR9238
CAT#: H532785
CAS#: 1416153-62-2
SR9238 is a potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXRβ and LXRα, respectively). SR9238 selectively inhibits live…
SR144528
CAT#: H532777
CAS#: 192703-06-3
SR144528 is a selective peripheral cannabinoid (CB2) receptor inverse agonist.
TRC051384
CAT#: H532774
CAS#: 867164-40-7
TRC051384 is a inducer of heat shock protein Hsp70. It reduces stroke-associated neuronal injury and increases survival in a rat model of transient is…
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