WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H575574
CAS#: 114414-02-7 (oxalate)
Description: Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.
Hodoodo Cat#: H575574
Name: Fluoxetine oxalate
CAS#: 114414-02-7 (oxalate)
Chemical Formula: C19H20F3NO5
Exact Mass: 399.13
Molecular Weight: 399.370
Elemental Analysis: C, 57.14; H, 5.05; F, 14.27; N, 3.51; O, 20.03
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 54910-89-3 (free base) 56296-78-7 (HCl) 114414-02-7 (oxalate)
Synonym: Fluoxetine oxalate
IUPAC/Chemical Name: N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine oxalate
InChi Key: CKOSCBUBUNGPOY-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H18F3NO.C2H2O4/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;3-1(4)2(5)6/h2-10,16,21H,11-12H2,1H3;(H,3,4)(H,5,6)
SMILES Code: CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2.OC(=O)C(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 399.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Di Rosso ME, Palumbo ML, Genaro AM. Immunomodulatory effects of fluoxetine: A new potential pharmacological action for a classic antidepressant drug? Pharmacol Res. 2015 Nov 28. pii: S1043-6618(15)00279-0. doi: 10.1016/j.phrs.2015.11.021. [Epub ahead of print] Review. PubMed PMID: 26644208.
2: Purgato M, Gastaldon C, Papola D, Magni LR, Rossi G, Barbui C. Drug dose as mediator of treatment effect in antidepressant drug trials: the case of fluoxetine. Acta Psychiatr Scand. 2015 Jun;131(6):408-16. doi: 10.1111/acps.12381. Epub 2014 Dec 11. Review. PubMed PMID: 25495269.
3: Wang Y, Yu L, Xie J, Chen J, Wei Q. Comparative efficacies of fluoxetine and paroxetine in major depression across varying acute-phase treatment periods: a meta-analysis. Asia Pac Psychiatry. 2014 Dec;6(4):353-62. doi: 10.1111/appy.12106. Epub 2013 Oct 22. Review. PubMed PMID: 24150924.
4: Stewart AM, Grossman L, Nguyen M, Maximino C, Rosemberg DB, Echevarria DJ, Kalueff AV. Aquatic toxicology of fluoxetine: understanding the knowns and the unknowns. Aquat Toxicol. 2014 Nov;156:269-73. doi: 10.1016/j.aquatox.2014.08.014. Epub 2014 Sep 6. Review. PubMed PMID: 25245382.
5: Cristancho MA, Thase ME. Drug safety evaluation of olanzapine/fluoxetine combination. Expert Opin Drug Saf. 2014 Aug;13(8):1133-41. doi: 10.1517/14740338.2014.933804. Epub 2014 Jun 27. Review. PubMed PMID: 24972823.