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Newest Products
WS6
CAT#: H530599
CAS#: 1421227-53-3
WS6 is a beta cell proliferation simulator. WS6 stimulates proliferation of both human beta and alpha cells while maintaining cellular viability and t…
KB-NB77-78
CAT#: H530597
CAS#: 1350622-33-1
KB-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673 (PKD1 inhibitor).
BAR-501
CAT#: H530595
CAS#: 1632118-69-4
BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR501 effectively reduced hepatic perfusion pressure and counteracted the…
MX69
CAT#: H407438
CAS#: 1005264-47-0
MX69 is a Dual Inhibitor of MDM2 and XIAP for Cancer Treatment.
S107 free base
CAT#: H530577
CAS#: 927871-76-9 (free base)
S107 is a Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the binding affinity of calstabin-1. Inhibits Ca leak from the sarcopla…
Thiomyristoyl
CAT#: H407437
CAS#: 1429749-41-6
Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. IC50 & Target: IC50: 28 nM (SIRT2). Thiomyristoyl showed broad antica…
GJ-103 free acid
CAT#: H530575
CAS#: 1459687-89-8 (free acid)
GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potentia…
GJ-103 sodium
CAT#: H530574
CAS#: 1459687-96-7 (sodium),
GJ103 sodium salt is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as…
BAY41-4109 racemic
CAT#: H530573
CAS#: 298708-79-9 (racemic)
BAY41-4109 racemic is a mixture of R-isomer of BAY41-4109 and S-isomer of BAY41-4109. BAY-41-4109 is a heteroaryldihydropyrimidine (HAP) antiviral c…
GDC-0077
CAT#: H206818
CAS#: 2060571-02-8
Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077…
Givinostat HCl
CAT#: H206814
CAS#: 199657-29-9 (HCl)
Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histone deacetylase inhibitor with potential anti-inflammatory, anti-an…
SR-18292
CAT#: H530568
CAS#: 2095432-55-4
SR-18292 is a proliferator-activated receptor-γ coactivator-1α (PGC-1α) inhibitor. SR-18292 reduces blood glucose, strongly increases hepatic insulin…
Iberdomide
CAT#: H528831
CAS#: 1323403-33-3 (free base)
Iberdomide, also known as CC-220, is potentially for the treatment of systemic lupus erythematosus. Iberdomide significantly reduced Ikaros and Aiolo…
NKY80
CAT#: H532352
CAS#: 299442-43-6
NKY80 is a inhibitor of adenylyl cyclase (AC). NKY80 exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM res…
Rimonabant free base
CAT#: H329640
CAS#: 168273-06-1 (free base)
Rimonabant, also known as SR141716 and A 281, is an anorectic anti-obesity drug. It is an inverse agonist for the cannabinoid receptor CB1. Its main a…
SB-756050
CAT#: H528518
CAS#: 447410-57-3
SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially for the treatment of type 2 diabetes.
Azvudine
CAT#: H528502
CAS#: 1011529-10-4
Azvudine, also known as FNC and RO-0622, is a reverse transcriptase inhibitor potentially for the treatment of HIV infection. Azvudine showed synergis…
MNI-137
CAT#: H532258
CAS#: 946619-21-2
MNI-137 is a selective negative allosteric modulator of group II mGlu receptors (IC50 values are 8.3 and 12.6 nM). MNI-137 displays no activity at mGl…
Puromycin Aminonucleoside
CAT#: H530551
CAS#: 58-60-6
Puromycin Aminonucleoside, also known as PAN, NSC3056, is useful in the study of human glomerular disease, and glomerular function and morphology. PAN…
MLN120B HCl
CAT#: H532254
CAS#: 1782573-78-7 (2HCl)
MLN-120B is a potent and effective inhibitor of IκB kinase beta subunit (IKKβ) with IC50 value of 20 μM. MLN-120B blocks multiple myeloma cell growth …
Ilginatinib maleate
CAT#: H528802
CAS#: 1354799-87-3 (maleate)
Ilginatinib, also known as NS-018, is a selective JAK2 inhibitor. Ilginatinib preferentially inhibits CFU-GM colony formation by bone marrow mononucl…
MLS1547
CAT#: H530549
CAS#: 315698-36-3
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin, and is an antagonist of dopamine…
GGTI-298 TFA
CAT#: H206802
CAS#: 1217457-86-7 (TFA)
GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential antitumor actrivity. GGTI-298 disrupts MAP kinase activation and…
9-Hydroxyellipticin free base
CAT#: H407424
CAS#: 51131-85-2 (free base)
9-hydroxyellipticine, also known as IGIG 929 and LS133324, is a potent cytotoxic and antitumor agent. Structurally, 9-hydroxyellipticine is a 9-hydro…
ML130
CAT#: H532189
CAS#: 799264-47-4
ML130 is an inhibitor of NOD1 (nucleotide-binding oligomerization domain containing 1).
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