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Newest Products
Exatecan mesylate
CAT#: H206786
CAS#: 169869-90-3 (mesylate)
Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits t…
AAI-101
CAT#: H527715
CAS#: 1001404-83-6 (free form)
Enmetazobactam, also known as AAI-101, is a novel β-lactam/β-lactamase inhibitor. AAI101 is similar in structure to tazobactam, with one important d…
CXA-10
CAT#: H527714
CAS#: 875685-46-4
CXA-10, also known as 10-Nitrooleic acid, is an endogenous nitro-fatty acid (NFA) modulator of Nrf2 and NF-κB potentially for the treatment of acute k…
GLPG0974
CAT#: H531847
CAS#: 1391076-61-1
GLPG0974 is a potent and selective FFA2 antagonist.
E4031 HCl
CAT#: H531769
CAS#: 113559-13-0 (2HCl)
E4031 selectively blocks hERG K+ channels. E4031 inhibits the rapid delayed-rectifier K+ current (IKr) and reversibly prolongs action potential dura…
AN0128
CAT#: H529412
CAS#: 872044-70-7
AN0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-α) inhibitor potentially for the treatment of atopic dermatitis. …
Fluzoparib
CAT#: H527603
CAS#: 1358715-18-0
Fluzoparib, also known as SHR3162, is a poly (ADP-ribose) polymerase inhibitor (PARP) inhibitor potentially for the treatment of solid tumours.
CYM-2503
CAT#: H531759
CAS#: 1308833-36-4
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor which potentiates galanin-induced IP1 production in vitro. CYM2503 potentiated t…
Oxipurinol
CAT#: H529402
CAS#: 2465-59-0
Oxipurinol is a xanthine oxidase inhibitor potentially for the treatment of heart failure and gout.
RPI-1
CAT#: H407385
CAS#: 269730-03-2
RPI-1 is an ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused growth arrest or regression in 81% treated tumors. Following treatmen…
BTB06584
CAT#: H530497
CAS#: 219793-45-0
BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 inhibited F1 Fo-ATPase activity with no effect on ΔΨm or…
CID16020046
CAT#: H513693
CAS#: 834903-43-4
CID16020046 is a selective GPR55 inverse agonist. CID16020046 is a G protein-coupled receptor that is weakly activated by some cannabinoids at nM con…
CHF-5074
CAT#: H513689
CAS#: 749269-83-8
CHF-5074, also known as CSP-1103, is a γ-secretase modulator. CHF-5074 reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM respectively. …
SP-187 HCl
CAT#: H527512
CAS#: 1333144-07-2 (HCl)
SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Pro…
CGP53353
CAT#: H513675
CAS#: 145915-60-2
CGP53353 is a selective inhibitor of PKCβII (IC50 values are 0.41 and 3.8 μM for PKCβII and PKCβI respectively). CGP53353 also inhibits prionogenic Su…
Proxalutamide
CAT#: H527507
CAS#: 1398046-21-3
Proxalutamide, also known as GT-0918, is an androgen receptor antagonist potentially for the treatment of metastatic castration-resistant prostate can…
Nifeviroc
CAT#: H529503
CAS#: 934740-33-7
Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection
BI6015
CAT#: H531571
CAS#: 93987-29-2
BI6015 is a small molecule antagonist of Hepatocyte nuclear factor 4α (HNF4α) that has been shown to repress the expression of known HNF4α target gen…
AZD6703 free base
CAT#: H531543
CAS#: 851845-37-9 (free base)
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).
BTA-9881
CAT#: H527408
CAS#: 1646857-24-0
BTA-9881, also known as AZD-9639 and MEDI-564, is a viral fusion protein inhibitor potentially for the treatment of respiratory syncytial virus infect…
AZD-1386
CAT#: H531517
CAS#: 942937-80-6 (NIH)
AZD1386 is an orally available antagonist of the transient receptor potential channel TRPV1. Note: Structure of this product was from NIH/NCATS web pa…
JX-06
CAT#: H407379
CAS#: 729-46-4
JX-06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 28, 49 and 313 nM for PDK2, PDK1 and PDK3, respec…
Davercin
CAT#: H530487
CAS#: 55224-05-0
Davercin, also known as Erythromycin Cyclocarbonate, is a bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. It inhibits protein…
SHP099 free base
CAT#: H407376
CAS#: 1801747-42-1 (free base)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. S…
XMD16-5
CAT#: H407372
CAS#: 1345098-78-3
XMD16-5 is a tyrosine kinase nonreceptor 2(TNK2) inhibitor. TNK2 mutations have been found in renal cancer cells and also in lung, ovarian and gastric…
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