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H522583
ICA-121431
featured
ICA-121431 is a potent, selective inhibitor of the human Nav1.3 and Nav1.1 voltage gated sodium chan…
H206542
INCB052793
INCB052793 is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1), with potential a…
H407243
ISS610
ISS610 is a STAT3 inhibitor. Aberrant activation of oncogenic signal transducer and activator of tra…
H319600
Iodopravadoline
featured
Iodopravadoline, also known as AM630, is an inverse agonist at the human cannabinoid CB1 receptor. …
H206507
Ivosidenib
featured
Ivosidenib, also known as AG-120 and RG-120, is an orally available inhibitor of isocitrate dehydrog…
H206502
INCB053914
INCB053914 is a novel, ATP-competitive, small molecule, pan-inhibitor of PIM kinases. INCB053914 is …
H319547
Ibiglustat
featured
Venglustat, also known as Ibiglustat, GZ402671, GZ-452; Genz-682452 and SAR402671, is a potent and s…
H319533
Ischemin sodium
Ischemin is a potent CBP bromodomain inhibitor. Schemin alters post-translational modifications on …
H319521
Indacaterol maleate
featured
Indacaterol is an ultra-long-acting beta-adrenoceptor agonist developed by Novartis. It was approved…
H317146
Indiplon
featured
Indiplon is a nonbenzodiazepine, hypnotic sedative. Indiplon works by enhancing the action of the in…
H407179
IPA-3
featured
IPA-3 is a potent and selective PAK1 inhibitor. IPA-3 inhibits the growth of liver cancer cells by s…
H522450
IT1t dihydrochloride
new
featured
IT1t is a potent and selective CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). IT1…
H522433
IM-12
featured
IM-12 is a cell-permeable indolylmaleimide that acts as a GSK-3β inhibitor. IM-12 is potent and sele…
H610231
Ibrutinib Interm 0441
featured
Ibrutinib Interm 0441 is a piperidine derivative with an amine protecting group. It may be used in t…
H407172
IN-1130
featured
IN-1130 is a highly selective small molecule ALK5 inhibitor with >100 fold selectivity over p38α and…
H522418
Intepirdine
featured
Intepirdine, also known as SB-742457 and RVT-101, is a selective 5-HT6 receptor antagonist with pot…
H206476
INCB054329
INCB054329, also known as INCB-54329, is a potent and selective BET protein inhibitor that targets …
H407163
IKK-16 (free base)
new
featured
IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for…
H522394
ISX-9
featured
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proliferation and d…
H317108
Ivabradine HCl
featured
Ivabradine is a novel medication used for the symptomatic management of stable angina pectoris. Ivab…
H317107
Isavuconazonium sulfate
featured
Isavuconazole (BAL4815; trade name Cresemba) is a triazole antifungal drug. Its prodrug, isavuconazo…
H522362
ITX-5061 HCl
ITX-5061 is a Hepatitis C Virus Entry Inhibitor or a scavenger receptor B1 antagonist. ITX 5061 has …
H206446
Ingenol disoxate
Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with I…
H407114
IACS-9571
featured
IACS-9571 is a potent and selective inhibitor TRIM24 and BRPF1. IACS-9571 has low nanomolar affiniti…
H407102
IU1
featured
IU1 is a selective USP14 inhibitor. IU1 prevents ventilator-induced lung injury in rats. IU1 inhibi…
H507210
Ivacaftor
featured
Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain muta…
H510297
Idalopirdine HCl
featured
Idalopirdine, also known as Lu AE58054 or Iladopirdine, is a potent and selective 5-HT6 receptor ant…
H511221
IDN-1965
IDN-1965 is a potent, broad-spectrum, irreversible caspase inhibitor. IDN-1965 is markedly effective…
H510287
ICI-118551 HCl
featured
ICI-118551, also known as ICI-118,551 and ICI 111581, is a selective beta-2 (β2) adrenergic receptor…
H315137
Istradefylline
featured
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been found to be usef…
H315227
Iguratimod
featured
Iguratimod is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesi…
H314224
Indacaterol
featured
Indacaterol is an ultra-long-acting beta-adrenoceptor agonist developed by Novartis. It was approved…
H314226
Icatibant
featured
Icatibant is a peptidomimetic drug consisting of ten amino acids, which is a selective and specific …
H406394
IWP-2
featured
IWP-2 is a potent WNT-3A inhibitor. IWP-2 can decrease MKN28 cell proliferation, migration and invas…
H406157
ISC-4
ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon t…
H406511
IRC-083927 HCl
IRC-083927 HCl is novel and potent microtubule inhibitor with potential anticancer activity. IRC-083…
H401512
IOX 2
featured
IOX 2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). IOX 2 displays ove…
H406376
INH-13
INH-13 is a Aurora inhibitor.
H402502
Indotecan
featured
Indotecan, also known as LMP400, is a novel selective and potent topoisomerase I inhibitor with pote…
H402501
Indimitecan
Indimitecan, also known as LMP776, is a novel topoisomerase I inhibitor.
H406192
INCB16562
INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 m…
H406518
Inauhzin
featured
Inauhzin is a potent SIRT inhibitor, which effectively reactivates p53 by inhibiting SIRT1 activity,…
H406491
Ilomastat
featured
Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloproteinase inhibitor…
H406510
IG-105
IG-105 is a potent microtubule inhibitor with potential anticancer activity. IG-105 inhibits microtu…
H406407
IC86621
featured
IC86621, also known as DNA-PK Inhibitor III, is potent DNA-Pk inhibitor with potential anticancer a…
H406334
Ibulocydine
Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and …
H401218
Ivaltinostat
Ivaltinostat, also known as CG200745, is a novel hydroxamate-based pan-histone deacetylase inhibitor…
H205917
Idasanutlin (RG7388)
featured
Idasanutlin, also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist wi…
H202180
Idronoxil
featured
Idronoxil, also known as Phenoxodiol, is a synthetic flavonoid derivative. Phenoxodiol activates the…
H205982
IRX5183
IRX5183, also known as NRX-195183, VTP-195183 and AGN195183, is an orally bioavailable retinoid aci…
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