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16
Angiogenesis
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BTK
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test3
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8
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2
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9
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11
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8
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8
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Androgen Receptor
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12
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19
GPCR & G Protein
Adenosine Receptor
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4
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5
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10
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20
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5
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17
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4
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9
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9
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16
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8
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4
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5
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2
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2
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EGFR Products
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H406574
WZ-8040
featured
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor with potential anticancer activi…
H406575
WZ-3146
featured
WZ-3146 is a covalent or irreversible pyrimidine-based EGFR inhibitor against EGFR T790M. WZ-3146 wa…
H406397
UNC2881
featured
UNC2881 is a potent Mer kinase inhibitor. UNC2281 inhibits steady-state Mer kinase phosphorylation w…
H406590
TPCA-1
featured
TPCA-1 is a potent IKK-2 inhibitor. TPCA-1 is also an effective inhibitor of STAT3 phosphorylation, …
H406473
SU5402
featured
SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast …
H401706
PP2
new
featured
PP2, also known as AG 1879, is a substance that has frequently been used in cancer research as a "se…
H406475
PD166866
featured
PD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, a…
H406476
PD089828
new
featured
PD089828 is a potent FGFR inhibitor, which inhibits human full-length fibroblast growth factor (FGF)…
H406105
PD-168393
featured
PD-168393 is a potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF …
H406486
MPT0E028
MPT0E028 is a novel N-hydroxyacrylamide-derived HDAC inhibitor, inhibited human colorectal cancer HC…
H406274
LCH-7749944
LCH-7749944, also known as GNF-Pf-2356, is a novel and potent PAK4 inhibitor, which effectively supp…
H406482
CNX-2006
featured
CNX-2006 is a potent, mutant-selective EGFR inhibitor with excellent in vitro activity in cells with…
H401220
Chrysophanic acid
featured
Chrysophanic acid (Chrysophanol ) is a a natural anthraquinone, has anticancer activity in EGFR-over…
H406498
CH5164840
CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity …
H401070
Allitinib tosylate
featured
Allitinib, also known as AST1306 and ALS 1306, is a potent, selective, irreversible ErbB2 and EGFR i…
H203186
Tesevatinib
featured
Tesevatinib, also known as XL647, EXEL-7647 and KD-019, is a n orally bioavailable small-molecule re…
H203181
Pilaralisib
featured
Pilaralisib, also known as XL147, is a Class 1 PI3K kinase family inhibitor with potential antineopl…
H202721
TAK-285
featured
TAK-285 is a novel dual erbB protein kinase inhibitor that specifically targets human epidermal grow…
H206217
PF-04929113 free base
featured
PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-shock protein 9…
H205736
SNX-2112
featured
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergoing multiple p…
H205937
Simotinib
Simotinib, also known as SIM6802, is a novel oral epidermal growth factor receptor tyrosine kinase i…
H206201
Pyrotinib
Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor of the epiderm…
H206199
Mavelertinib
featured
Mavelertinib, also known as PF-06747775, is an orally available inhibitor of the epidermal growth fa…
H202190
Pelitinib
featured
Pelitinib, also known as EKB569 and WAY-172569, is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhi…
H202174
PD-153035 free base
featured
PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectivel…
H202172
Mirdametinib
featured
Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which…
H201470
Neratinib
featured
Neratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HE…
H206800
Mubritinib
featured
Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under development by Take…
H200944
AV-412 Tosylate
new
featured
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase inhibitor with…
H201562
INSM-18
featured
Nordihydroguaiaretic acid, also known as INSM-18, NDGA and NSC 4291, is a naturally occurring antiox…
H205846
Poziotinib
featured
Poziotinib , also known as HM781-36B and NOV120101, is an orally bioavailable, quinazoline-based pan…
H205950
Falnidamol
new
featured
Falnidamol, also known as BIBX 1382, is a pyrimido-pyrimidine with antitumor activity. BIBX 1382 inh…
H206157
Nazartinib
featured
Nazartinib, also known as EGF816 and NVS-816, is an orally available, irreversible, third-generation…
H200841
CUDC-101
featured
CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal grow…
H200820
CP-724714
featured
CP-724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP-724,714 s…
H200810
CP-547632
featured
CP-547632, also known as PAN-90806, is as a potent inhibitor of the VEGFR-2 and basic fibroblast gr…
H205796a
CO1686-DA
CO1686-DA, is a CO1686 precursor, also a des-acryl analogue of CO1686. CO1686 is an orally available…
H200600
Canertinib HCl
featured
Canertinib, also known as CI1033 and PD183805, is a potent ErbB inhibitor for the treatment of cance…
H200533
BMS-690514
BMS-690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4,…
H204676
BIIB028
BIIB028 is a small-molecule inhibitor of heat shock protein (Hsp) 90 with potential antineoplastic a…
H205923
BAY1082439
featured
BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha…
H206042A
AZD9291DA HCl salt
AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed pr…
H206182
AZD3759
featured
AZD3759 is also known as zorifertinib. It is an orally available inhibitor of the epidermal growth …
H206137
Naquotinib free base
featured
Naquotinib, also known as ASP8273, is an orally available, irreversible, third-generation, mutant-se…
H200291
Tucatinib
featured
Tucatinib, also known as Irbinitinib, ARRY-380 and ONT-380, is a n orally bioavailable inhibitor of …
H200121
AG-490
new
featured
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal tr…
H200500
Afatinib free base
featured
Afatinib, also know as BIBW 2992, is an orally bioavailable dual receptor tyrosine kinase (RTK) inhi…
H200100
AEE-788
featured
AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosp…
H200080
Aderbasib
featured
Aderbasib, also known as INCB007839, is a sheddase inhibitor, is also an orally bioavailable inhibit…
H100800
Tamoxifen citrate
featured
Tamoxifen, also known as ICI 46474, is an antagonist of the estrogen receptor in breast tissue via i…
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