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Akt Products
or product name starting with:
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H509120
YM201636
featured
YM201636 is an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, and ca…
H500408
BX912
new
featured
BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. BX912 blocks PDK1/Akt signaling in tu…
H406366
WYE-125132
featured
WYE-125132, also known as WYE-132, is a highly potent, ATP-competitive, and specific mTOR kinase inh…
H401810
Bemcentinib
featured
Bemcentinib, also known as BGB-324 or R428, is a selective small molecule inhibitor of Axl kinase, w…
H406158
PX-316
PX-316 is a AKT inhibior. PX-316, when administered intraperitoneally to mice at 150 mg/kg, inhibits…
H406324
PKI-402
featured
PKI-402 is a selective, reversible, ATP-competitive, equipotent inhibitor of class I phosphatidylino…
H401705
PHT-427
featured
PHT-427 is an AKT inhibitor that inhibits AKT and PDPK1 at low micromolar concentrations in numerous…
H401691
PF-4942847
PF-4942847 is a novel oral Hsp90 inhibitor, which is a candidate for clinical development in TNBC by…
H401685
AKT-0286
AKT-0286, also known as Lig1, is an APT competitor inhibitor of AKR kinase. AKT-0286 was first descr…
H401562
NVP-BEP800
new
featured
NVP-BEP800, also known as BEP-800, is a novel, fully synthetic, orally bioavailable inhibitor that …
H406304
MG-132
featured
MG132 is a specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM) . It re…
H406435
Methylthioadenosine
featured
Methylthioadenosine, also known as MTA and 5'- Methylthioadenosine, is a naturally occurring sulfur-…
H406297
Mahanine
Mahanine, a carbazole alkaloid (occurs in the edible part of Micromelum minutum, Murraya koenigii an…
H406368
L-2286
L-2286 is a novel PARP inhibitor. L-2286 exerted significant protective effect against ischemia-repe…
H406441
KU-60019
featured
KU-60019 is a potent and selective ATM inhibitor. KU-60019 is 10-fold more effective than KU-55933 a…
H558212
KP372-1
KP372-1 is a synthetic small molecule AKT inhibitor. KP372-1 is consisted of two isomers: KP372-1 A …
H406157
ISC-4
ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon t…
H406156
GSK2334470
featured
GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM), …
H406424
GGTI-2154
GGTI-2154 is a geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2154 results not only in halti…
H406145
ETP-46321
featured
ETP-46321 is a potent and orally bioavailable PI3K α, δ inhibitor with potent biochemical and cellul…
H406335
Deguelin
featured
Deguelin is a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumo…
H401220
Chrysophanic acid
featured
Chrysophanic acid (Chrysophanol ) is a a natural anthraquinone, has anticancer activity in EGFR-over…
H401212
CCT128930
featured
CCT128930 is a novel ATP-competitive AKT inhibitor discovered using fragment- and structure-based ap…
H401156
BRN-103
BRN-103 was found to suppress the VEGF-induced phosphorylation of VEGF receptor 2 (VEGR2) and the ac…
H406235
BMS-554417
BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activit…
H406369
BGP-15 HCl
new
featured
BGP-15 is a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplat…
H406439
AZ7328
AZ7328 is a potent and selective AKT inhibitor. AZ7328 inhibited proliferation and AKT substrate pho…
H406398
API-1
featured
API-1 is a potent Akt inhibitor, which induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degr…
H406403
APcK110
APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1…
H401010
A-443654
A-443654 is a potent and selective AKT inhibitor. A-443654 induces rapid Akt Ser-473 phosphorylation…
H205795
ZSTK474
featured
ZSTK474 is a novel orally applicable phosphoinositide 3-kinase-specific inhibitor that strongly inhi…
H206015
XL-418
XL-418 is a selective, orally active small molecule, targeting protein kinase B (PKB or AKT) and rib…
H203010
Triciribine
featured
Triciribine, also known as VQD-002, is a potent AKT inhibitor and a cell-permeable tricyclic nucleos…
H205672
SR13668
SR13668 is an Akt inhibitor, is also a n orally bioavailable indole-3-carbinol (I3C) analogue inhibi…
H206217
PF-04929113 free base
featured
PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-shock protein 9…
H205736
SNX-2112
featured
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergoing multiple p…
H202601
SF1126
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF…
H200860
Ridaforolimus
featured
Ridaforolimus, also known as AP23573, is an investigational small-molecule inhibitor of mTOR, a prot…
H202360
Sonolisib (PX-866)
featured
Sonolisib, also known as PX-866, is a small-molecule wortmannin analogue inhibitor of the alpha, gam…
H202226
PF-04691502
new
featured
PF-04691502 is a PI3K/mTOR kinase inhibitor , is also an agent targeting the phosphatidylinositol 3 …
H202070
Oleandrin
featured
Oleandrin, also known as PBI-05204 , is a lipid soluble cardiac glycoside with potential antineoplas…
H205934
Nifurtimox
featured
Nifurtimox is a 5-nitrofuran and is used to treat diseases caused by trypanosomes including Chagas d…
H206164
M2698 HCl
MSC2363318A, also known as M2698, is an orally available inhibitor of the serine/threonine protein …
H205885
MRK003
MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myel…
H205743
MLN-1117
featured
Serabelisib (also known as MLN1117, INK1117, and TAK-117) is an orally bioavailable inhibitor of the…
H205495
Sapanisertib (MLN0128)
featured
Sapanisertib, also known as TAK-228, MLN0128 and INK128, is a TORC1/2 inhibitor, is an orally bioava…
H201920
MKC-1
new
featured
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with poten…
H525682
MK-2461
featured
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met. MK-2461 inhibited in …
H205856
ME-344
ME-344 is an active metabolite of NV-128, a novel flavonoid small molecule inhibitor of the mammalia…
H201795
LY294002
featured
LY294002 is a morpholine derivative of quercetin. It is a potent inhibitor of phosphoinositide 3-kin…
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