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16
Angiogenesis
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19
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Adenosine Receptor
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4
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10
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20
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17
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2
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ERK Products
or product name starting with:
A
B
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D
E
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N
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Z
H404210
U0126
featured
U0126 is a potent and selective non-competitive inhibitor of MAP kinase. Inhibits MEK-1 and MEK-2 (I…
H406226
SNX-7081
NX-7081 is a novel small molecule inhibitor of Hsp90, which blocks components of inflammation, inclu…
H406198
RO5068760
RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)…
H406212
PF-04880594
featured
PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerization in those epit…
H406304
MG-132
featured
MG132 is a specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM) . It re…
H401483
GW5074
featured
GW5074 is a c-Raf inhibitor. GW5074 has no direct effect on the activities of several apoptosis-asso…
H401220
Chrysophanic acid
featured
Chrysophanic acid (Chrysophanol ) is a a natural anthraquinone, has anticancer activity in EGFR-over…
H204730
XL-281
XL281, also known as BMS-908662 , is an orally active, small molecule Raf kinase inhibitor with pote…
H206012
WX-554
WX-554 is an orally available small molecule mitogen-activated protein kinase kinase (MAP2K, MAPK/ER…
H205638
TAK-733
featured
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential …
H200300
Selumetinib (AZD6244)
featured
Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineop…
H202462
RO4987655
featured
RO4987655, also known as CH4987655, is an orally active small molecule, targeting mitogen-activated…
H202432
RDEA-436
RDEA-436 is a second-generation mitogen-activated ERK kinase inhibitor for the treatment of cancer. …
H206168
PLX8394 (removed)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf (BRAF) protein …
H202172
Mirdametinib
featured
Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which…
H205852
Encorafenib
featured
Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antin…
H205482
GSK-2256098
featured
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential ant…
H206065
Ravoxertinib
featured
Ravoxertinib also known as GDC-0994, GDC994 and RG7842, is an orally available inhibitor of extracel…
H203185
Cobimetinib
new
featured
Cobimetinib, also known as GDC-0973 and XL-518, RG 7420, is an orally bioavailable small-molecule in…
H205772
GDC-0623
featured
GDC-0623, also known as G-868, is an orally active, selective MEK inhibitor with potential antineopl…
H206008
Diazepinomicin
Diazepinomicin, also known as TLN-4601 and BU 4664L, is a small-molecule inhibitor of the RAS/RAF/MA…
H200771
CI-1040
featured
CI-1040, also known as PD184352, is a MEK inhibitor, which demonstrated in vivo activity in preclini…
H200770
RAF-265 (CHIR-265)
featured
RAF-265, also known as CHIR-265, is an orally bioavailable small molecule with potential antineoplas…
H205903
RXDX-105 (CEP-32496)
featured
RXDX-105, also known as Agerafenib, CEP-32496 and AC013773, is an orally available v-raf murine sarc…
H200313
AZD-8330
featured
AZD8330, also known as ARRY704 and ARRY424704, is an orally active, selective MEK inhibitor with po…
H205859
AS703988
AS703988, also known as MSC201510B, is an orally bioavailable small-molecule inhibitor of mitogen-ac…
H200297
Pimasertib
featured
Pimasertib, also known as AS703026, SAR245509, MSC1936369B, is an orally bioavailable small-molecule…
H200121
AG-490
new
featured
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal tr…
H100490A
Lapatinib (free base)
featured
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatini…
H401680
PD98059
featured
PD98059 also known as PD-98059, is a potent and selective inhibitor of MAP kinase kinase (also know…
H406556
FR180204
featured
FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which ma…
H406645
CCT196969
featured
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. CCT196969 blocked g…
H406644
CCT241161
featured
CCT241161 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. CCT241161 blocked g…
H510338
AM251
featured
AM251 is a cannabinoid receptor antagonist. AM251 improves recognition memory in rats and produces n…
H406208
TDZD-8
featured
TDZD-8 is a serine/threonine glycogen synthase kinase 3beta (GSK-3beta) inhibitor. GSK-3beta is abun…
H201458
Trametinib
featured
Trametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen-activated prot…
H207181
ONC-201
Dordaviprone, also known as ONC-201 and TIC10, is a potent, orally active, and stable small molecul…
H202272
PLX4720
featured
PLX4720 is a 7-azaindole derivative that inhibits B-Raf(V600E) with an IC(50) of 13 nM, defines a cl…
H202228
PF-562271 Besylate
featured
PF-562271 Besylate, also known as PF-562,271 and PF-271, is an orally bioavailable small molecule an…
H205737
Debio-0932
featured
Debio 0932, also known as CUDC-305, is a novel heat shock protein 90 (HSP90) inhibitor with strong a…
H100946
Lapatinib ditosylate
featured
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatini…
H406578
SCH772984
featured
SCH772984 is an potent and selective ERK inhibitor with potential anticancer activity. SCH722984 sho…
H202030
NOV-002
featured
NOV-002, also known as Glutathione disulfide, GSSG; oxidized glutathione, is a dimer of glutathione …
H406561
Ulixertinib (BVD-523)
featured
Ulixertinib, also known as BVD-523 and VRT752271, is an inhibitors of ERK protein kinase. Downmodula…
H406531
Kobe0065
featured
Kobe0065 is a small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effe…
H406580
Kobe-2602
featured
Kobe2602, is analog of Kobe0065 , is is a potent and selective RAS inhibitor, which exhibit inhibito…
