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16
Angiogenesis
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BTK
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test3
demo333
8
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2
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9
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11
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8
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8
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12
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19
GPCR & G Protein
Adenosine Receptor
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4
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5
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10
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20
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5
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17
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4
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9
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9
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16
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8
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4
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5
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2
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2
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Products starting with 'A'
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H406291
AC17
AC17, a novel 4-arylidene curcumin analog, is a potent 19S deubiquitinase inhibitors with great pote…
H406416
ABT-100
new
featured
ABT-100 is an orally bioavailable farnesyltransferase inhibitor. ABT-100 inhibited proliferation of …
H406470
ABC294735
ABC294735 is a dual SK1/SK2 inhibitor with potential anticancer activity.
H406287
AAL-993
featured
AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50…
H406213
AAE871
AAE871 is a type I FLT3 inhibitor.
H406362
A-966492
new
featured
A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme wit…
H401012
A-674563
featured
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays acti…
H401010
A-443654
A-443654 is a potent and selective AKT inhibitor. A-443654 induces rapid Akt Ser-473 phosphorylation…
H401002
A83-01
featured
A-83-01 is an ALK inhibibitor. It was found that A-83-01 inhibited the transcriptional activity indu…
H206118
Apabetalone
featured
Apabetalone, also known as RVX-208, is a potent inhibitor of BET bromodomains. RVX-208 functions by…
H200944
AV-412 Tosylate
new
featured
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase inhibitor with…
H205517
APTO253 free base
featured
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with…
H205485
Apoptone
featured
Apoptone, also known as HE3235, is an orally bioavailable adrenal steroid analogue with potential an…
H205830
Avadomide free base
featured
Avadomide, also known as CC-122, is an orally available pleiotropic pathway modulator with potential…
H205949
Afeletecan HCl
Afeletecan, also known as BAY 56-3722, is a water-soluble camptothecin derivative conjugated to a c…
H205822
Avanbulin
Avanbulin, also known as BAL27862, is a novel synthetic potent inhibitor of tubulin polymerization t…
H200315
AZM-475271
featured
AZM475271 is orally Src tyrosine kinase inhibitor with potential anticancer and antimetastatic activ…
H206059
Azaserine
featured
Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic properties, …
H206108C
AZD9291-345
AZD9291-345 is a compound which has a molecule weight 345, and structurally related to AZD9291.
H206042A
AZD9291DA HCl salt
AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed pr…
H200313
AZD-8330
featured
AZD8330, also known as ARRY704 and ARRY424704, is an orally active, selective MEK inhibitor with po…
H200312
AZD-8055
featured
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic a…
H200311
AZD-7762
featured
AZD-7762 is a synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemose…
H205820
AZD7451
AZD7451, also known as AZ12607092, is a tropomyosin receptor kinase (TRK) inhibitor with potential …
H206220
AZD-6918
AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates t…
H200427
AZD-6126
AZD6126, also known as ANG-453, a water-soluble phosphate prodrug of N-acetylcolchinol with potentia…
H206089
AZD-5582
featured
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI motif of Smac. AZD5…
H200426
AZD5438
featured
AZD5438 is a potent inhibitor of cyclin-dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nm…
H200425
AZD-4992
AZD-4992 is a bioactive chemical.
H200424
AZD4877 HCl
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activit…
H206215
AZD-4769
AZD-4769, also known as L 674573, is a leukotriene biosynthesis inhibitor.
H206040
AZD3965
featured
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of …
H206182
AZD3759
featured
AZD3759 is also known as zorifertinib. It is an orally available inhibitor of the epidermal growth …
H206098
AZD-3409
AZD-3409 is a potent prenyl transferase inhibitor. AZD-3409 showed higher potency than lonafarnib. T…
H200421
AZD-1152HQPA
featured
AZD-1152 HQPA, also known as AZD-2811, is a potent and selective Aurora B inhibitor (IC50 of 0.37 nM…
H205948
AZD-0424
AZD-0424 is an orally bioavailable small molecule tyrosine kinase inhibitor that targets both Abl an…
H206150
ATR-101 HCl
featured
ATR-101, also known as PD-132301 (a free base) or PD-132301-2 (a HCl salt), is in clinical developme…
H200340
Atiprimod (free base)
Atiprimod is an orally bioavailable small molecule belonging to the azaspirane class of cationic amp…
H200330
Atamestane
Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irrever…
H205786
Ataluren (PTC124)
featured
Ataluren, also known as PTC124, is an investigational new drug designed to enable the formation of a…
H200322
AT-9283 free base
featured
AT9283 is a multikinase inhibitor, is also a small-molecule inhibitor of several kinases with potent…
H205818
ASP9521
featured
ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase typ…
H205859
AS703988
AS703988, also known as MSC201510B, is an orally bioavailable small-molecule inhibitor of mitogen-ac…
H200296
AS-605240
featured
AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory disea…
H205817
AS101
AS101, also known as Ossirene, is a synthetic non-toxic tellurium derivative, structurally similar …
H200310
Arzoxifene HCl
Arzoxifene, also known as LY353381, is a synthetic aromatic derivative with anti-estrogenic properti…
H205900
ARRY-382
ARRY-382 is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor …
H200290
ARRY-300 (MEK300)
ARRY-300, also know as MET300, is a potent MET inhibitor, currently in clinical trials.
H205816
ARQ-761
ARQ-761 is a soluble prodrug of beta-lapachone with potential antineoplastic and radiosensitizing ac…
H204440
ARQ-736
ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer ce…
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