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16
Angiogenesis
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19
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4
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10
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20
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5
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17
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2
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PI3K Products
or product name starting with:
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H205482
GSK-2256098
featured
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential ant…
H205739
GSK1059615
featured
GSK1059615 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. P…
H206085
GRD081
GRD081 is a dual PI3K/mTOR inhibitor. The no-observed-adverse-effect level (NOAEL) of GRD081 was 1mg…
H205472
GGTI-2418
featured
GGTI-2418, also known as PTX100, is a synthetic peptidomimetic inhibitor of geranylgeranyltransferas…
H201300
Spisulosine
Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynom…
H205836
DS-7423
DS-7423 is an orally bioavailable inhibitor of phosphatidylinositol 3 kinase (PI3K) and mammalian ta…
H205961
DS-3078a
DS-3078a is an orally bioavailable inhibitor of raptor-mTOR protein complex (TORC1) and rictor-mTOR …
H205924
Fimepinostat
featured
CUDC-907, also known as fimepinostat, is an orally bioavailable inhibitor of both phosphoinositide 3…
H205747
CH5132799
featured
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a strong inhibi…
H205829
CC-115
new
featured
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamyci…
H200492
BGT226 free base
featured
BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. P…
H200491
Dactolisib
featured
Dactolisib, also known as BEZ235, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inh…
H206151
BAY1125976 HCl
BAY1125976 is an orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein k…
H205923
BAY1082439
featured
BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha…
H200312
AZD-8055
featured
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic a…
H200281
Miransertib free base
featured
Miransertib, also known as ARQ 092, is an oral activie, potent and selective AKT inhibitor with IC50…
H200272
OSU-03012
featured
OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown…
H204310
AMG-319
featured
AMG-319, also known as ACP319, is a highly selective, potent, and orally bioavailable small molecule…
H202870
Temsirolimus
featured
Temsirolimus is an ester analog of rapamycin. Temsirolimus binds to and inhibits the mammalian targe…
H406155
IC-87114
featured
IC-87114 is a potent and ATP-competitive PI3K p110δ isoform-selective inhibitor (IC50 = 60 nM). It I…
H205481
Uprosertib
featured
Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/t…
H205966
Acalisib
featured
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catal…
H204930
Tucidinostat HCl
featured
Tucidinostat (also known as HBI-8000, Chidamide, and CS-055) is a benzamide type inhibitor of histon…
H406323
PIK-294
featured
PIK-294 is a highly selective inhibitor of the phosphoinositide 3-kinase (PI3K) p110δ with an IC50 v…
H205670
GSK-690693
featured
GSK690693 is a pan-AKT kinase inhibitor, is also a n aminofurazan-derived inhibitor of Akt kinases w…
H205669
Capivasertib
featured
AZD5363, also known as Capivasertib, is an orally available inhibitor of the serine/threonine protei…
H406554
CZC24832
featured
CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in…
H205746
Taselisib (GDC0032)
new
featured
Taselisib, also known as GDC0032 or RG7606, is a selective, potent, orally bioavailable inhibitor of…
H406661
CAL-130
CAL-130 is a potent and selective PI3K gamma and delta inhibitor with potential anticancer activity.…
H406643
ISA-2011B
featured
ISA-2011B is a PIP5Kα (Phosphatidylinositol-4-phosphate 5-kinase-α) inhibitor. The overexpression of…
H406637
GNE-317
featured
GNE-317 is a potent and selective PI3K inhibitor with potential anticncer activity. GNE-317 targets …
H406260
AZD8186
new
featured
AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential ant…
H202895
TGX-221
featured
TGX-221 is a potent, selective, and cell membrane permeable inhibitor of the PI3K p110β catalytic su…
H202228
PF-562271 Besylate
featured
PF-562271 Besylate, also known as PF-562,271 and PF-271, is an orally bioavailable small molecule an…
H406432
PF-4708671
featured
PF-4708671 is a novel cell-permeable inhibitor of S6K1. PF-4708671 specifically inhibits the S6K1 is…
H202133
Palomid-529
featured
Palomid 529, also known as P529, is a novel PI3K/Akt/mTOR inhibitor. Palomid 529 (P529) inhibits the…
H205891
Kevetrin HCl
featured
Kevetrin ( thioureidobutyronitrile), is a water-soluble, small molecule and activator of the tumor s…
H205744
Duvelisib (IPI-145)
featured
Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and poten…
H200586
Idelalisib (CAL-101)
featured
Idelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and ant…
H205844
GSK2636771
featured
GSK2636771 is an orally bioavailable, substituted benzimidazole inhibitor of the class I phosphoinos…
H205480
Omipalisib
featured
Omipalisib, also known as GSK2126458, is a small-molecule pyridylsulfonamide inhibitor of phosphatid…
H201072
Golvatinib
featured
Golvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyt…
H205470
GDC-0980 (Apitolisib)
featured
Apitolisib, also known as GDC-0980 and RG7422; or GNE390, is a dual PI3 kinase/mTOR inhibitor, is al…
H205467
Ipatasertib (GDC-0068)
featured
Ipatasertib, also known as GDC-0068, is an orally bioavailable inhibitor of the serine/threonine pro…
H205737
Debio-0932
featured
Debio 0932, also known as CUDC-305, is a novel heat shock protein 90 (HSP90) inhibitor with strong a…
H204780
Alpelisib
featured
Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhi…
H204690
Buparlisib (BKM120)
featured
Buparlisib, also known as BKM120, is an orally bioavailable specific oral inhibitor of the pan-class…
H204570
Copanlisib free base
featured
Copanlisib, also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) inhibitor. Copan…
H406268
AZD6482
featured
AZD6482 is a potent, selective and ATP competitive PI3Kβ inhibitor (IC(50) 0.01 μm). AZD6482 inhibit…
H204520
Vistusertib (AZD-2014)
featured
Vistusertib, also known as AZD2014, is an orally bioavailable inhibitor of the mammalian target of r…
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